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Posted 259 Days Ago in: Training, Genetics


3473 Posted 307 Days Ago in: Genetics, Nutrition

Is Low-Sodium Diet Good For Everyone?

Sodium is a key component of many foods regularly consumed by people on a daily basis and although health recommendations often advise otherwise, there is still not enough done to stop people from adding excessive amount of salt to their foods. A major problem with this is that sodium is contained in many regular food products, added to increase the flavor and taste of foods that would otherwise possibly be too bland. But although we all regularly consume sodium every single day, the question is whether or not turning to a low sodium diet is healthy for people. Research has shown that 1.65 million deaths from cardiovascular causes that occurred in 2010 were attributed to sodium consumption above a reference level of 2.0 g per day.

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3438 Posted 360 Days Ago in: Training, Genetics, Nutrition

How can we tell you about your DNA from one little swab?

The 20,000+ genes that make up your genome hold countless clues to understanding the fundamental processes of human life. Ever since the completion of the Human Genome Project, our knowledge of how we are made has developed at an unprecedented rate. In our case, it opened a new realm of information about your individual fitness and nutrition needs, easily accessible from one little mouth swab.

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3432 Posted 383 Days Ago in: Genetics

Can genes affect your taste?

We all have people who we know: friends, family, acquaintances, and work colleagues who all have distinctly different tastes when it comes to food. Some like it hot, while others…not so much. Others devour sugary treats in the blink of an eye, and without flinching, while other people wince at the sight of a rich quadruple chocolate dessert; politely declining the offer. The list goes on, but other than getting a “taste” for certain foods, are there other factors at play?

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3418 Posted 423 Days Ago in: Training, Nutrition

The Ultimate Guide To Supplements: Part 1

When you’ve finally settled into your routine and are training regularly, you’ll start hearing about supplements you can take to increase your performance, recovery, and response to various types of exercise. The industry has exploded to the point where it is worth billions, and companies are constantly marketing products in new ways that promise to activate new muscles and make you bigger and stronger than ever before. But do these supplements actually work?

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3405 Posted 455 Days Ago in: Training, Genetics, Industry News, Nutrition

Sport Science Review 2016 Part 2

As part of my job role at DNAFit, I read a lot of different scientific papers from a wide range of disciplines within sports science. At the end of 2015, I reviewed the best bits of research I had come across in 2015 (click for Part One and Part Two), and in this two-part article I will share with you the papers that had the biggest impact on me in 2016.

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3391 Posted 502 Days Ago in: Training, Genetics, Nutrition

Am I Normal? A review of over 17,000 DNAFit Results

When running customers through their DNAFit reports, a common question I am asked is “Are my results normal?” This is a tough question to answer, because it’s hard to define what normal actually is. For all the single nucleotide polymorphisms (SNPs) we test for, each individual genotype is quite common; the least common genotype occurs in about one in twenty people, which means that in the UK over three million people who have that specific version.

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3387 Posted 511 Days Ago in: Genetics, Nutrition

Gene in Focus - Part 30: ADRB3

This week we are investigating ADRB3, a gene which appears in our fat sensitivity panel. This gene encodes for beta-3-adrenergic receptors, which are located mainly is fat tissue. They play a role in breaking down fat for use as energy, and a small change in this gene, known as a single nucleotide polymorphism (SNP), is thought to determine how well we can tolerate saturated fats.

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3382 Posted 525 Days Ago in: Training, Genetics

Gene in Focus: Part 28 - PPARGC1A

This week to turn our attention to PPARGC1A, or as we call it at DNAFit, “the one with the long name”. This gene encodes for a protein called peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1a), which causes some of the positive changes that occur in our body following exercise. One of the ways that exercise can lead to improvements is through something called mitochondrial biogenesis, which is the production of new mitochondria within the muscle itself.

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3377 Posted 539 Days Ago in: Genetics, Nutrition

Gene in Focus: Part 26: FABP2

This week we turn our attention to FABP2, a gene that appears in both the carbohydrate and saturated fat parts of our reports. This gene creates a protein called Fatty Acid Binding Protein-2, which is found in our small intestines. FABP2 binds to the various different fatty acids, and allows them to be absorbed into the body.

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3375 Posted 545 Days Ago in: Training

The Guide To Training Over 40: Starting Out

We know how you feel… You’re older and have never really committed to training, or you may feel as though the prospect of getting in the gym or running on the road is too daunting – that’s it too late. It’s not. Although it may seem as though starting now may do more harm than good, it’s actually pretty much the opposite.

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3373 Posted 549 Days Ago in: Training, Genetics

The Guide To Training Over 40: What Happens To Your Body When You Get Older?

There are pros and cons as you get older, and a little more decline if you’re into training, but there are also interventions that you can make to adapt to changes and maintain a lifestyle of efficiency long into what is perceived as old age. First, we’ll take you through the changes that occur when you get older:

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3367 Posted 567 Days Ago in: Genetics

Gene in Focus: Part 22 - BDKRB2

Our attention this week is on another gene that is found as part of our Peak Performance algorithm, which has been shown to enhance response to a resistance training programme. The gene we are focusing on this week is BDKRB2, which encodes for the bradykinin B2 receptor, which comprises one of the pathways through which bradykinin can exert its influence. Bradykinin itself is a protein that causes dilation (widening) of blood vessels, making it easier for blood to move to certain areas of the body. The effects of this gene are closely linked to the of ACE, which is a gene we met earlier in this series. Angiotensin-Converting Enzyme, which is produced by the ACE gene, also breaks down bradykinin, such that ACE II genotypes (who have lower levels of ACE) should theoretically have higher levels of bradykinin.

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3359 Posted 588 Days Ago in: Genetics

Gene in Focus: Part 19: AD1HC

If you’ve ever heard that a glass of red wine per day is good for your heart, this is truer for some people than others. Plenty of research has shown that moderate amounts of alcohol consumption can protect against risks of heart disease. For example, a study published in 1997 found that alcohol intake was associated with a protective effect against coronary heart disease in a sample of almost 130,000 people – this effect was present for both beer and wine. A second study, again from 1997, found that in both men and women, rates of cardiovascular disease were 30-40% lower in those consuming at least one drink per day compared to abstainers.

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3358 Posted 591 Days Ago in: Training, Genetics

Genetics or training - what is the secret to becoming a star athlete?

Amongst all the records, achievements and scandals at Rio 2016, a small piece of history was written. Leila, Liina and Lily Luik from Estonia became the first identical triplets to compete against each other in a single event – the marathon. If this wasn’t proof enough that athletic talent runs in the family, there were at least 36 sets of siblings competing in the Rio Olympics, showcasing family dominance at the Summer Games.

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3356 Posted 595 Days Ago in: Training, Genetics

Gene in Focus - Part 18: PPARA

In this week's edition of our blog, we look at PPARA, a gene that affects how well we can respond to different types of training, and as a result appears in our power-endurance algorithm. PPARA creates peroxisome proliferator-activated receptor alpha, a protein which activates other genes, as well as being a regulator of fatty acid oxidation during exercise. The gene is activated when our cells aren’t getting enough energy, such as when we fast, or when we take part in exercise that uses up our energy stores, such as endurance exercise.

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3354 Posted 600 Days Ago in: Genetics

Is this the end of calorie counting?

When we think of calorie counting we think of reducing the amount of food you eat every single meal, carefully measuring it on a mental scale and extending lunch breaks spent analysing how many calories every single item of food you aim to consume. When you look at it this way, it’s a very stressful experience. But it doesn’t have to be. There’s always more than one way to skin a cat, or, in this case, trim the fat.

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3353 Posted 602 Days Ago in: Training, Genetics

Gene in Focus - Part 17: VEGF

This week, we look at a gene that plays a role in both the power/endurance and aerobic trainability aspect of our report. This gene is VEGF, and it creates Vascular Endothelial Growth Factor, which plays a role in the creation of new blood vessels. This is a useful adaptation to aerobic training, because more blood vessels around the muscle mean better, more efficient transport of oxygen, as well as fuel sources such as carbohydrates and fats, to the muscle; this in turn improves how well a person can use oxygen and exercise aerobically. When we exercise, our muscle cells quite often don’t get as much oxygen as they need. This causes the VEGF gene to be “turned on”, with transcription upregulated and more VEGF formed – leading to this increased growth of new blood vessels.

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3349 Posted 612 Days Ago in: Training, Genetics

8 biggest mistakes you can make if you want bigger muscles

Whatever your fitness goal is, we all get discouraged when a heavy training regime brings us no or very little effect, especially if we can’t figure out why. Well, fear no more because DNAFit are here to bring you some mistakes that you may be making in the gym that are the reasons why your muscle building exercises aren’t working at their optimum level.

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3341 Posted 620 Days Ago in: Training, Genetics

Professional athletes and stress- how do they cope?

Everyone around the world is getting sport fever. The Olympics are back! Here at DNAFit we’ve done a little investigation into what role stress plays in athletic performance during the Olympics, and how the world’s top athletes deal with pressure to still go for the gold in their quest to be the best. We’ve drawn from a variety of theories to paint you a comprehensive picture of the complicated relationship between athletic performance and stress and the different ways in which it manifests.

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3339 Posted 622 Days Ago in: Genetics

Gene in Focus: Part 14 - SOD2

SOD2 is the gene that creates Manganese Superoxide Dismutase-2 (MnSOD2), an antioxidant found in the mitochondria – small “cells within our cells” which are where our body produces energy for both movement and everyday life. The enzyme helps to convert free radicals, which can cause damage to the mitochondria, into oxygen and hydrogen peroxide.

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